Location: 
Kardinal Wendel Haus
Mandlstrasse 23, 80802 Munich

Day 2: WEDNESDAY, 16th

09:00 – 10:15   Session 4: Novel target discovery in CAA 

                Chair: Marcel Verbeek, Radboud University Medical Center, Nijmegen, The Netherlands

09:00 – 09:25   Exome and single-cell RNA sequencing: new insights into CAA and SVD

                Andrew Yang, Stanford University, USA

09:25 – 09:50   Proteomics Discovery Tools for CAA
                Nicholas Seyfried, Emory University, Atlanta, USA

09:50 – 10:15   Novel targets derived from histopathologic analysis

                Julie Schneider, Rush University, Chicago, USA

10:15 – 10:50   Selected Oral Abstracts 

                Exploring the role of vasomotion in promoting brain clearance in CAA

                Orla Bonnar, Massachusetts General Hospital and Harvard Medical School, Boston,                     USA

                Evaluation of Basigin and VE-Cadherin as novel blood-brain barrier dysfunction                     biomarkers in CAA

                Arno Stellingwerf, Radboud University Medical Center, Nijmegen, The Netherlands

                Characterization of CSF biomarkers in patients with CAA

                Aida Fernández Lebrero, Hospital Del Mar, Barcelona, Spain

10:50 – 11:20   Coffee break

11:20 – 12:35   Session 5: Interface with clinical conditions

                Chair: Gabor Petzold, University Hospital Bonn, Germany

11:20 – 11:45   CAA and hypertension

                Marco Pasi, University of Tours, France

11:45 – 12:10   CAA and atrial fibrillation

                Andreas Charidimou, Boston University Medical Center, USA

12:10 – 12:35   CAA and anti-amyloid immunotherapy

                Mariel Kozberg, Massachusetts General Hospital / Harvard Medical School, Boston,                   USA

12:35 – 14:30   Lunch break & Poster viewing

14:30 – 15:05   Selected Oral Abstracts 

                Chair: Gabor Petzold, University Hospital Bonn, Germany

                ApoE ε4 homozygosity is associated with an increased incidence of CAA and a                   breakdown of the glymphatic system

                Natalie Beschorner, German Center for Neurodegenerative Diseases, Bonn, Germany

                Functional investigations of meningeal lymphatic drainage in CAA

                Hsin-Hsi Tsai, National Taiwan University Hospital, Taipei, Taiwan

                Blood amyloid-β fragments in CAA: a prospective cohort study

                Francesco Bax, Massachusetts General Hospital and Harvard Medical School, Boston,                 USA

15:05– 16:20    Session 6: Emerging imaging approaches to CAA 

                Chair: Stefanie Schreiber, Otto-von-Guericke University, Magdeburg, Germany

15:05 – 15:30   High-frequency MR imaging of CAA

                Anna Dewenter, LMU Hospital, Munich, Germany

15:30 – 15:55   Imaging progression of hereditary and sporadic CAA

                Thijs van Osch, Leiden University Medical Center, The Netherlands 

15:55 – 16:20   Radiologic-histopathologic correlations of CAA markers

                Valentina Perosa, Massachusetts General Hospital / Harvard Medical School, Boston,                   USA

16:20 – 16:50   Coffee break

16:50 – 17:25   Selected Oral Abstracts 

               
                Non-contrast CT markers associated with CAA

                Sanne Schriemer, Leiden University Medical Center, The Netherlands

                Enlarged perivascular spaces in the centrum semiovale in patients with vascular                   cognitive impairment

                Geert Jan Biessels, University Medical Center Utrecht,      
                Molecular and microstructural alterations in CAA-related hemorrhagic manifestations

                Elif Gokcal, Harvard Medical School, Boston, USA

17:25 – 18:30   Poster viewing

18:00 – 19:30   Internal Board Meeting ICAA Association