7th International CAA Conference

30 SEPTEMBER | 1 OCTOBER

Welcome to the 7th International Cerebral Amyloid Angiopathy Conference. We have crafted a program that features cutting-edge research, translational ideas for clinical trials, and new knowledge on prevention and treatment of manifestations of CAA such as hemorrhagic stroke.

REGISTER
Eric Smith, MD, MPH
Steven Greenberg M.D. Ph.D.
Mark van Buchem MD, PhD
253
days
19
hours
54
min
45
sec

Message from the Chair

Dear participant of the ICAA online Conference,

 

Please take notice of the following:


 

The 7th International CAA Conference has appointed ConventionALL Management Inc. from Calgary, Alberta, Canada as the Virtual Event Organizers. As a registered conference participant you will receive an email in the next week with a username and password, with a link to the Event Day Hub. This Virtual Event Day Hub will have access to all the presentations, research posters and speaker information. If you have any questions regarding access to the 7th International CAA Conference please contact

Kyla Arneson, kyla@conventionall.com.  

 

 

  For any further questions don’t hesitate to contact the Conference desk, office@icaaconference.org  

 

regards,

 

Eric Smith, MD, MPH

Professor of Neurology, University of Calgary

Chair, 7th International CAA Conference Organizing Committee

 

 

This meeting is endorsed by the European Stroke Organization. It is open to all who are interested in cerebrovascular diseases

www.eso-stroke.org

www.eso.kenes.com

European Stroke Organisation

 

 

Program online conference

WEDNESDAY SEPTEMBER 30

Eastern Daylight Time

Central European Summer Time

Topic

Speaker

9:00-9:10

15:00-15:10

Opening Remarks

Eric Smith, University of Calgary

Symposium: Cerebral Amyloid Angiopathy as a Transmissable Proteinopathy

Chairs:  Hamid Sohrabi (Edith Cowan University), David Werring (University College London)

9:10-9:30

15:10-15:30

Keynote: Prion diseases 

John Collinge, University College London

9:30-9:45

15:30-15:45

Iatrogenic CAA: An Emerging Clinical Phenomenon

Gargi Banerjee, University College London

 

 

Oral Abstracts

 

9:45-9:55

15:45-15:55

MFG-E8 (Lactadherin) accumulates in Aβ-affected cortical vessels in Cerebral Amyloid Angiopathy

Paula Marazuela, Universitat Autònoma de Barcelona

9:55-10:05

15:55-16:05

Early impairments in vasomotion in a mouse model of cerebral amyloid angiopathy

Mariel Kozberg, Massachusetts General Hospital

Symposium: New Therapeutic Strategies for CAA

Chairs: Charlotte Cordonnier (Université de Lille), Dar Dowlatshahi (University of Ottawa)

10:15-10:30

16:15-16:30

RNA Inhibition Therapies

Roger Lane, Ionis Pharmaceuticals

10:30-10:45

16:30-16:45

Minocycline as a Therapeutic Agent for CAA

Marieke Wermer, Leiden University Medical Center

10:45-11:00

16:45-17:00

Design considerations for CAA trials

Steven Greenberg, Mass General Hospital

 

 

Oral Abstracts

 

11:00-11:10

17:00-17:10

Patterns of White Matter Hyperintensities define Vascular and Parenchymal Amyloid Burden: a big data imaging approach

Chia-Ling Phuah, Washington University School of Medicine & Barnes-Jewish Hospital

11:10-11:20

17:10-17:20

Cerebral Amyloid Angiopathy is Associated with Affective Dysregulation, Impulse Dyscontrol, and Apathy

Eric Smith, University of Calgary

11:20-11:30

17:20-17:30

Sensitivity of the Edinburgh Criteria for Lobar Intracerebral Hemorrhage in Hereditary Cerebral Amyloid Angiopathy

Ellis van Etten, Leiden University Medical Center

11:30-11:40

17:30-17:40

Idiopathic Primary Intraventricular Hemorrhage and Cerebral Amyloid Angiopathy

Alvin Das, Massachusetts General Hospital

Panel Discussion

Chairs: Eric Smith (University of Calgary), Mark van Buchem (Leiden University Medical Center)

11:50-12:20

17:50-18:20

Q&A on CAA

Steven Greenberg (Mass General Hospital), Charlotte Cordonnier (University of Lille), David Werring (University College London), Susanne van Velow (Mass General Hospital)

12:20

18:20

Presentation of Poster Prizes

 
       

THURSDAY OCTOBER 1

Eastern Daylight Time

Central European Summer Time

Topic

Speaker

9:00-9:05

15:00-15:05

Welcome

Eric Smith, University of Calgary

Symposium: Biomarkers of CAA

Chairs: Sandra Black (University of Toronto), Ashkan Shoamanesh (McMaster University)

9:05-9:20

15:05-15:20

Biofluid biomarkers of AD and CAA

Ralph Martins, Macquarie University

9:20-9:30

15:20-15:30

PET imaging of CAA

Christopher Rowe, University of Melbourne

9:30-9:40

15:30-15:40

Biomarker Evolution in Presymptomatic HCHWA-D Mutation Carriers

Jeroen van der Grond, Leiden University Medical Center

 

 

Oral Abstracts

 

9:40-9:50

15:40-15:50

Cerebral amyloid angiopathy is associated with decreased functional brain connectivity

Nadieh Drenth, Leiden University Medical Center

9:50-10:00

15:50-16:00

Composite plasma biomarker score distinguished pre-symptomatic Dutch-type hereditary cerebral amyloid angiopathy mutation carriers from non-carriers

Pratishtha Chatterjee, Macquarie University,

School of Medical Health and Sciences, Edith Cowan University

       

Symposium: Neurovascular Unit Response to CAA

Chairs: Marcel Verbeek (Radboud University), Cheryl Wellington (University of British Columbia)

10:10-10:25

16:10-16:25

Microvascular architecture in relation to blood flow

Sylvie Lorthois, Institut de Mécanique des Fluides de Toulouse

10:25-10:40

16:25-16:40

Imaging the neurovascular unit response to microbleed

Andrew Shih, University of Washington

10:40-10:55

16:40-16:55

High resolution MRI of microvessel structure/function

Jaco Zwanenburg, University Medical Center Utrecht

 

 

Oral Abstracts

 

10:55-11:05

16:55-17:05

Spatial Differences in Cerebrovascular Reactivity to Carbon Dioxide Between Patients with Cerebral Amyloid Angiopathy (CAA) and Healthy Controls

Andrew Beaudin, University of Calgary

11:05-11:15

17:05-17:15

Loss of cholinergic innervation differentially affects eNOS-mediated cerebral blood flow, intramural periarterial drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

Shereen Nizari, University College London

       

Symposium: Beta-Amyloid Clearance via Perivascular and Other Drainage Routes

Chairs: JoAnne McLaurin (University of Toronto), Julie Schneider (Rush University)

11:25-11:40

17:25-17:40

Cerebrospinal Fluid and Blood Flow Oscillations in Sleep

Laura Lewis, Boston University

11:40-11:55

17:40-17:55

Perivascular Spaces as a Pathway for Amyloid Clearance

Erik Bakker, VU University Medical Center Amsterdam

11:55-12:10

17:55-18:10

Microvascular dynamics and amyloid clearance

Susanne van Veluw, Mass General Hospital

 

 

Oral Abstracts

 

12:10-12:20

18:10-18:20

Cerebral amyloid angiopathy aggravates perivascular clearance

Shin Heun Kim, Korea Advanced Institute of Science and Technology

12:20-12:30

18:20-18:30

Cell-type specific transcriptional changes in Dutch-type hereditary cerebral amyloid angiopathy

Tom Metz, Leiden University Medical Center

 

 

 

 

 

 

 

 

12:30

18:30

Closing Remarks

 

 

             
               
               
               
Calgary Boston CET Australia (Perth) Comments
7 am – 11 am 9 am – 1 pm 3 pm – 7 pm 9 pm – 1 am same day  
noon – 4 pm 2 pm – 6 pm 8 pm – 12 am 2 am – 6 am next day in Australia
4 pm – 8 pm 6 pm – 10 pm 12 am – 4 am 6 am – 10 am next day in Australia
12 am – 4 am 2 am – 6 am 8 am – 12 pm 2 pm – 6 pm    
             
               
               
               
               
               
               
               

Reservation Desk

Please register for the 7th International Cerebral Amyloid Angiopathy Conference, to be held online on September 30 and October 1. The theme of the conference is Converting Knowledge to Action: Designing Clinical Trials for CAA.

 

This conference will be of interest to basic scientists, clinical researchers, and clinicians. The online conference will feature 3 hours of programming each day for two days, additionally with online poster presentations with asynchronous chat with poster presenters. Fourteen lectures will cover topics including new therapeutic approaches to CAA, vascular and perivascular clearance mechanisms for beta-amyloid, pathophysiology of the neurovascular unit in CAA, neuroimaging biomarkers, clinical trial design, and the new diagnostic criteria, the Boston Criteria 2.0.

 

The reduced registration fees are 50 euros for regular registration, 25 euros for students and trainees. Student registration is open to anyone enrolled in a university graduate or undergraduate program, medical residency, or post-doctoral fellowship program (including MD post-doctoral fellows).

 

Register here

This meeting is endorsed by the European Stroke Organization. It is open to all who are interested in cerebrovascular diseases.

European Stroke Organisation

www.eso-stroke.org

www.eso.kenes.com

abstract submission

 

*****ABSTRACT SUBMISSION DESK CLOSED*****

 

Dear All,
 
We are pleased to announce that the virtual online International CAA conference of 30 September | October, 2020, is accepting abstracts for presentation. The deadline for submissions is July 24, 2020
 
Any basic or clinical science related to CAA is eligible for presentation at the meeting. This includes basic research on causes and mechanisms of CAA, the relationship between CAA and Alzheimer’s Disease, epidemiology, neuropathology, biomarkers, therapeutics, clinical trials, outcomes, and clinical care. 
 
Abstracts will be accepted for oral presentation at the virtual conference, or for presentation at an online e-poster.
 
We look forward to helping you disseminate your research on CAA.
 
Sincerely yours,
Eric Smith
Mark van Buchem 
Steve Greenberg
 

 

Submission Guidelines
–        All abstracts must be submitted via office@icaaconference.org ONLY. Abstracts sent by fax will not be accepted.

–        All abstracts should be written in English.
–      It is the responsibility of the presenting author and the submitter to review the submission status & information and correct them. Submitters are responsible for any typo error in the abstract.
–        The presenting author’s name should be underlined.
–        The abstract should be limited to;
o   400 words (text only), or
o   300 words and up to 2 images or tables
 
Important Dates
Call for Abstract                                June 18, 2020
Abstract Submission Due                 July 17, 2020
 


Scientific Program Committee

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Organizing Committee 2020

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