Location: 

Kardinal Wendel Haus
Mandlstrasse 23, 8-0802 Munich, Germany

Day 1: TUESDAY, 15th

08:15 – 09:00   Registration and coffee

09:00 – 10:05   Opening Session

09:00 – 09:10   Martin Dichgans: Welcome to Munich

                LMU Hospital, Institute for Stroke and Dementia Research, Munich, Germany

09:10 – 09:20   Steven Greenberg: Welcome to the 9^th ICAAA conference

                Chair ICAA Association, Massachusetts General Hospital / Harvard Medical                           School, Boston, USA

09:20 – 10:05   Opening Lecture

                Late onset AD risk variants in ABI3 and vascular dysfunction

                Christian Haass, LMU Hospital, Munich, Germany

10:05 – 10:30   Coffee break

10:30 – 11:45   Session 1: Challenging questions in iatrogenic cerebral amyloidosis 

                Chair: Masahito Yamada, Kudanzaka Hospital, Tokyo, Japan

10:30 – 10:55   Biology of amyloid transmission

                Mathias Jucker, DZNE, Tübingen, Germany

10:55 – 11:20   Is amyloid transmissible via blood?

                Gustaf Edgren, Karolinska Institute, Stockholm, Sweden

11:20 – 11:45   Iatrogenic transmission of Alzheimer disease

                Gargi Banerjee, University College London, UK

11:45 – 12:20   Selected Oral Abstracts
 

                Clinical-radiological presentation and natural history of iatrogenic cerebral amyloid                 angiopathy

                Simon Fandler-Höfler, Medical University of Graz, Austria

                Blood-brain barrier leakage in cerebral amyloid angiopathy

                Sabine Voigt, Leiden University Medical Center, The Netherlands

                In vivo imaging of gadolinium-based contrast agent leakage in patients with CAA

                Hilde van den Brink, Massachusetts General Hospital, Boston, USA

12:20 – 14:20    Lunch break & Poster viewing

14:20 – 15:35    Session 2: CAA-ri, ARIA, and mechanisms of immune-related vessel injury 

                 Chair: Ellis van Etten, Leiden University Medical Center, The Netherlands

14:20 – 14:45    Modeling CAA-ri in rodents

                 Bill van Nostrand, University of Rhode Island, USA

14:45 – 15:10    Role of perivascular macrophages in CAA-ri / ARIA

                 Costantino Iadecola, Weill Cornell Medical College, New York, USA

15:10 – 15:35    Role of complement in CAA-ri / ARIA

                 Martine Grenon, Harvard Medical School, Boston, USA

15:35 – 16:10    Selected Oral Abstracts 

                 ARIA-pathology correla1ons in 5xFAD mice treated with an1-Ab immunotherapy

                 Ed Plowey, Biogen Inc., Cambridge MA, USA

                 Associations between the Edinburgh diagnostic criteria for CAA-associated lobar                    ICH and recurrent ICH

                 Rustam Al-Shahi Salman, University of Edinburgh, Edinburgh, UK

                 Perivascular tau in autopsy cases with definite CAA

                 Valentina Perosa, Harvard Medical School, Boston, USA

16:10 – 16:40    Coffee break

16:40 – 17:55    Session 3 – Glymphatic function and vessel physiology in health and disease                      

                 Chair: Susanne van Veluw, Massachusetts General Hospital / Harvard Medical School,                  Boston, USA

16:40 – 17:05    Brain barriers, glymphatic clearance, and CAA

                 Leon Smyth, Washington University in St. Louis, USA

17:05 – 17:30    Cerebrovascular function and glymphatic clearance in animal models

                 Leon Munting, Leiden University Medical Center, The Netherlands

17:30 – 17:55    Leveraging contrast-based MRI for the quantification of glymphatic clearance in                    the human brain

                 Swati Rane Levendovszky, University of Washington Medical Center, Seattle, USA

19:30 – 22:30              Conference Dinner and networking Event

                           “Ratskeller – Alte Küferei”, Marienplatz 8